NUR 530
Week 1 Discussion 1
Select one of the following discussion prompts to address:
•
Analyze how calcium and phosphate are hormonally regulated and describe the
pathophysiology, clinical manifestations, evaluation and treatments for
hypercalcemia and hypocalcemia.
•
Describe the clinical manifestations, similarities, and differences of the following
vitamin deficiencies: niacin, riboflavin (B2), thiamine (B1), folate, vitamin B12, vitamin
B6, pantothenic acid (B5), biotin, vitamin C, vitamin K, vitamin E, vitamin A, and
vitamin D.
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment of
metabolic acidosis and metabolic alkalosis. Discuss how and when each of the
buffer systems responds to compensate/correct for acid-base imbalances.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 1 Discussion 2
Select one of the following discussion prompts to address:
•
Discuss the inherited mutation genes BRCA and BRCA 2, their prevalence, risks for
different cancers, and recommended surveillance screenings for those with a
confirmed genetically inherited mutation. What are your thoughts on genetic testing?
•
Discuss the inherited disorders familial adenomatous polyposis and hereditary
nonpolyposis colorectal cancer, their prevalence, responsible genes, and screening
recommendations for those confirmed with the inherited gene.
•
Analyze the evidence regarding the contribution of genetics and/or environment for
obesity, Alzheimer’s disease, alcoholism, and schizophrenia. In the case of obesity,
what impact does it have in our society today?
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 2 Discussion 1
Select one of the following discussion prompts to address:
•
Describe autoimmunity and the process by which the body develops a hyperimmune
or hypersensitive reaction to its own tissues. Consider lupus. It has been found that
those living with lupus are at higher risk for other autoimmune diseases such as
rheumatoid arthritis. Explore this interrelationship, known as overlap diseases, in the
following website, Molly’s Fund (Links to an external site.) and discuss the
implications for care.
•
Describe active versus passive immunity and provide an example of each. Define
antibody or immunoglobulin and describe the five molecular classes of
immunoglobulins and their function(s) in the body by providing a pathologic example
for an increase of each immunoglobulin (e.g., IgEâ€â€parasitic infection). Why are
some viruses inaccessible to antibodies after initial infection?
•
Describe and discuss transmission, pathogenesis, clinical manifestations, treatment
and prevention of HIV/AIDS.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 2 Discussion 2
Select one of the following discussion prompts to address:
•
Describe how normal cells go through the process of transformation into cancer
cells. How is this process different from DNA mutations associated with genetic
disease? Review this article on genetics and identify (Links to an external site.)how
the mutations differ.
•
Stress and Disease: Describe the physiologic effects on body systems of increased
cortisol levels released during the stress response.
•
Review the current research evidence from credible, scholarly sources and
summarize the results of the effects and health risks of electromagnetic radiation
(from cellular and cordless telephones, microwaves, computers, fluorescent lights,
radar, and electronic equipment).
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 3 Discussion 1
Select one of the following discussion prompts to address:
•
Consider the impact of spinal cord injury and the potential scope of lifetime disability
and sequelae associated with spinal cord injury. The greatest challenge facing the
neuroscience community involves developing therapy that will allow damaged nerve
tissue to be regrown and regenerated. Reflect on this article (Links to an external
site.)and discuss the importance of Schwann cells and their impact on damaged
axons.
•
Describe the genetic components, pathophysiology, and major neurologic features
of neurofibromatosis, Cri du chat syndrome, Tay-Sachs disease, and Parkinson
disease (early onset).
•
Define dementia of Alzheimer type (DAT) and describe the pathophysiology, clinical
manifestations, evaluation and treatment.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 3 Discussion 2
Select one of the following discussion prompts to address:
•
Consider the following scenario: Your patient has suffered from schizophrenia for
two decades and has received classic dopaminergic treatments since the onset of
illness. The latest research supporting use of the glutamatergic model has not been
tried on your patient, and there is an opportunity for your patient to enter clinical
trials utilizing glutamate-based treatments. Your patient suffers significant executive
function impairment and memory impairment. Do you recommend participation in
the clinical trial? Why or why not?
•
Discuss the pathophysiology of cerebrovascular accidents (CVAs)â€â€thrombotic,
embolic, hemorrhagic, and lacunarâ€â€their incidence and prevalence, clinical
manifestations, evaluation, and treatment.
•
Discuss the characteristics of common headachesâ€â€migraine, cluster, and tensionâ€â€
and describe their evaluation and treatment options. What prevention strategies
would you advise?
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 4 Discussion 1
Select one of the following discussion prompts to address:
•
Consider the long-term effects of hyperglycemia as seen in poorly controlled
diabetes. Consider factors that lead to good or poor compliance in regimens
designed to decrease hyperglycemia and improve health outcomes in
diabetics. Review this article (Links to an external site.)and identify the key factors
that can interfere with compliance.
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment of
two diseases of the posterior pituitary–syndrome of inappropriate antidiuretic
hormone secretion (SIADH) and diabetes insipidus (DI).
•
Discuss Grave’s Disease and the systemic manifestations and treatment of
hyperthyroidism. Describe the pathophysiology, clinical manifestations, evaluation,
and treatment of hypothyroidism.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 4 Discussion 2
Select one of the following discussion prompts to address:
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment of
polycystic ovary syndrome (PCOS).
•
Discuss common causes of galactorrhea and describe the pathophysiology, clinical
manifestations, evaluation, and treatment of galactorrhea.
•
Describe benign prostatic hypertrophy (BPH) and discuss the pathogenesis, clinical
manifestations, evaluation, and treatment of BPH.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 5 Discussion 1
Select one of the following discussion prompts to address:
•
Describe childhood acute lymphocytic leukemia (ALL) and G6PD deficiency and the
incidence, pathophysiology, clinical manifestations, evaluation, and treatment of
each.
•
Describe the morphology of erythrocytes, the mechanism, and primary cause of the
following anemias: Pernicious anemia, folate deficiency anemia, iron deficiency
anemia, thalassemia, and sickle cell anemia.
•
Describe the most common causes and provide examples
for neutrophilia, neutropenia, eosinophilia (i.e., eosinophilia caused by asthma, hay
fever, or parasitic
infection), eosinopenia, basophilia, monocytosis, monocytopenia, lymphocytosis,
and lymphocytopenia.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 5 Discussion 2
Select one of the following discussion prompts to address:
•
Discuss the development of coronary artery disease (CAD) and the links to
dyslipidemia, hypertension, cigarette smoking, diabetes mellitus, obesity, and
sedentary lifestyle. Review the current scholarly literature, and describe the markers
and testing of cardiovascular risk and prevention and treatment recommendations.
•
Describe the pathophysiology of acute rheumatic fever and rheumatic heart disease,
and discuss the pathophysiology, clinical manifestations, evaluation (include the
revised Jones Criteria), and treatment of rheumatic fever.
•
Review and summarize the Joint National Committee (JNC) recommendations for
the prevention, detection, evaluation, and treatment of high blood pressure. Review
the recommendations made by the American Diabetes Association’s 2016
Standards of Medical Care in Diabetes for the control of high blood pressure and
summarize the treatment recommendations.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 6 Discussion 1
Select one of the following discussion prompts to address:
•
Discuss the pathophysiology, clinical manifestations, evaluation, and treatment of
cystic fibrosis. Discuss the potential impact of gene therapy on CF and the ethical
dimensions in treating this life-limiting disease.
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment of
asthma (include the National Asthma Education and Prevention Program
guidelines).
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment of
tuberculosis or pneumonia.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 6 Discussion 2
Select one of the following discussion prompts to address:
•
Summarize acute kidney injury (AKI), include the RIFLE criteria for acute renal
dysfunction/failure, and describe the pathophysiology, clinical manifestations,
evaluation, and treatment.
•
Describe the stages of chronic kidney disease, and summarize the pathophysiology,
clinical manifestations, evaluation, and treatment.
•
Discuss common causes of acute pyelonephritis, and describe the pathophysiology,
clinical manifestations, evaluation, and treatment.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 7 Discussion 1
Select one of the following discussion prompts to address:
•
Describe the pathophysiology of celiac disease, clinical manifestations, evaluation,
and treatment. What are the differences between non-celiac gluten sensitivity
and celiac disease?
•
What trends, if any, have you noticed among the following conditions? Describe
the pathophysiology, clinical manifestations, evaluation, and treatment
of gastroesophageal reflux disease (GERD), peptic ulcer disease, and gastritis.
•
Describe the chronic relapsing inflammatory bowel diseases (ulcerative colitis
and Crohn disease), and summarize the pathophysiology, clinical manifestations,
evaluation, and treatment recommendations for each.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 7 Discussion 2
Select one of the following discussion prompts to address:
•
Review this Mayo Clinic overview (Links to an external site.). Define fibromyalgia
and describe the pathophysiology, clinical manifestations, evaluation, and treatment.
Comment on advances in diagnosis and management of this disorder that debunk
the idea that the disorder is “in the patient’s head.â€Â
•
Define osteoporosis and describe the risk factors, pathophysiology, clinical
manifestations, evaluation, prevention, and treatment.
•
Describe osteoarthritis (OA) and rheumatoid arthritis (RA), and discuss the
pathophysiology, clinical manifestations, evaluation, and treatment for each.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 8 Discussion 1
Select one of the following discussion prompts to address:
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment
of atopic dermatitis, impetigo contagiosum, tinea capitis, thrush,
and molluscum contagiosum.
•
Describe the pathophysiology, clinical manifestations, evaluation, and treatment(s)
for psoriasis, lichen planus, pemphigus, seborrheic keratosis, and actinic keratosis.
•
Describe the incubation periods, onset of prodromal symptoms, duration, and
characteristics of rashes and other clinical symptoms of the following viral diseases:
rubella (German measles), rubeola (measles), roseola (exanthema subitum),
and varicella (chickenpox). List the CDC-recommended childhood vaccination
schedule applicable.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
Week 8 Discussion 2
Select one of the following discussion prompts to address:
•
Describe multiple organ dysfunction syndrome (MODS) and summarize the
pathophysiology, clinical manifestations, evaluation, and treatment.
•
Describe the characteristics of first-, second-, and third-degree burns and the rule of
nines assessment tool to estimate burn percentages. Discuss the recommended
strategies for initial and maintenance fluid replacement after a major burn injury.
•
Summarize the causes, clinical manifestations, evaluation, and treatment for
cardiogenic, hypovolemic, neurogenic, anaphylactic, and septic shock.
Use at least one scholarly source other than your textbook to connect your response to
national guidelines and evidence-based research in support of your ideas.
In your peer replies, please reply to at least one peer who chose a different discussion
prompt.
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